Which condition is most likely to benefit from OSA splints?

The condition most likely to benefit from OSA splints is mild to moderate obstructive sleep apnea (OSA). OSA splints, commonly known as mandibular advancement devices (MADs), are specifically designed to reposition the jaw slightly forward, which helps to keep the airway open during sleep. This repositioning can significantly reduce the frequency and severity of apneic episodes for patients experiencing mild to moderate OSA, as the airway obstruction typically occurs in these cases due to the collapse of the soft tissues at the back of the throat.

In cases of severe OSA, while some patients might benefit from OSA splints, treatment usually requires more intensive interventions, such as continuous positive airway pressure (CPAP) therapy, due to the higher risk associated with significant airway obstruction.

Central sleep apnea involves a lack of respiratory effort due to issues in the brain's control of breathing and is not typically treated with OSA splints, as the cause is not related to airway obstruction. Thus, the splints are not beneficial for central sleep apnea or all forms of sleep apnea, since their effectiveness is tailored to correcting the airway collapse characteristic of mild to moderate OSA.